Table 2 Transcriptional changes in the dorsal hippocampus of rats following 5-min contextual novelty exploration. Information on the fold change in Group NOV-Veh relative to Group CC, the p-value from Welch’s t-test, and the results of a standardized effect size analysis, which includes Hedges’ g correction. CI, 95% confidence interval. The upregulated genes are highlighted in bold
Gene symbol | Gene expression | Welch’s t-test | Standardized effect size | ||
|---|---|---|---|---|---|
fold change | p value | Hedges’ g | Lower CI | Upper CI | |
Tnik | 0.91 | < 0.001 | –2.272 | –3.370 | –1.137 |
Arhgef2 | 0.95 | 0.001 | –1.695 | –2.681 | –0.670 |
Arc/Arg3.1 | 1.85 | 0.001 | 1.895 | 0.838 | 2.918 |
Fos | 3.97 | 0.003 | 1.700 | 0.679 | 2.688 |
Ap3s2 | 1.09 | 0.007 | 1.352 | 0.391 | 2.285 |
Cfl1 | 0.93 | 0.012 | –1.192 | –2.103 | –0.255 |
Agap3 | 1.07 | 0.013 | 1.211 | 0.271 | 2.124 |
Rasgrf2 | 0.91 | 0.016 | –1.138 | –2.041 | –0.207 |
Wasf1 | 0.97 | 0.019 | –1.104 | –2.000 | –0.179 |
Capzb | 0.96 | 0.021 | –1.089 | –1.987 | –0.165 |
Homer1a | 1.17 | 0.022 | 1.131 | 0.201 | 2.033 |
Camk2a | 0.95 | 0.023 | –1.066 | –1.961 | –0.145 |
Dusp10 | 1.11 | 0.048 | 0.909 | 0.008 | 1.787 |