Skip to main content

Table 3 Shared gene expression changes in mouse and rat. A list of gene expressions affected by contextual novelty, shared between the mouse and rat dorsal hippocampus. Gene name, function, fold change, and statistical significance (Welch’s t-test) are included for both species. *p < 0.05; **p < 0.01. The upregulated genes are highlighted in bold

From: Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study

Gene symbol

Function

Mouse

Rat

CC vs. NOV

CC vs. NOV-Veh

Fold change

Significance

Fold change

Significance

Homer1a

Positive control, PSD scaffolding protein

1.77

**

1.17

*

Arhgef2

Rho/Rac GEF, Regulate actin assembly

1.10

**

0.95

**

Agap3

ARF6-GAP, Regulate AMPA receptor trafficking

1.10

*

1.07

*