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Fig. 3 | Molecular Brain

Fig. 3

From: Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila

Fig. 3

Knockdown of dnrx-1 in R8 postsynaptic targets also affected the maintenance of Rh5 restriction. Frozen sections of adult heads expressing lexAop-nSyb-spGFP1-10 under control of the Rh5-specific driver Rh5-lexA, were stained with anti-GFP (green) and MAb24B10 (magenta). (A and A’) Wild type (n = 10). (B and B’) Flies in which dnrx-1 was specifically knocked down in R8 postsynaptic targets by placing UAS-nrx-1-RNAi-GD2619 under control of the ortC1–3-GAL4 driver (n = 12). (C) The percentage of Rh5-positive axons were increased significantly when dnrx-1 was specifically knocked down in R8 postsynaptic targets. ***p < 0.001. Error bars indicate SD. Scale bar, 20 μm

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