Fig. 1

Disruption of either NLGN3-NRXNs or NLGN3-PTPδ pathway has little effect on social novelty recognition. a Experimental time-course for the five-trial social novelty test. b Mean social interaction time in wild-type (WT) and Nlgn3^hse mutant mice. c Mean social interaction time in WT and Nlgn3^mf mutant mice. Data are presented as mean ± SEM. *P < 0.05, **P < 0.001, and ***P < 0.0001, Paired two-tailed t-test