Fig. 2

Impaired social conditioned place preference in Nlgn3^mf mutant mice. a Schematics of the sCPP test. b Scatter plot of time spent in the "social" chamber during the pre- and post-test for WT and Nlgn3^hse mutant mice. There was no significant difference between WT and Nlgn3^hse mutant mice (RM two-way ANOVA: time effect, F (1, 94) = 6.040, P = 0.0158; genotype effect, F (1, 94) = 0.01403, P = 0.9060; time × genotype interaction, F (1, 94) = 0.01029, P = 0.9194). c Scatter plot of time spent in the "social" chamber during the pre- and post-test for WT and Nlgn3^mf mutant mice. There was no significant difference between WT and Nlgn3^mf mutant mice (RM two-way ANOVA: time effect, F (1, 74) = 5.129, P = 0.0265; genotype effect, F (1, 74) = 0.1167, P = 0.7336; time × genotype interaction, F (1, 74) = 1.272, P = 0.2630). Summarized data are presented as mean ± SEM. *P < 0.05, Paired two-tailed t-test