Fig. 4

Little effect on spatial working memory by disruption of either NLGN3-NRXNs or NLGN3-PTPδ pathway. Spatial working memory of the Nlgn3^hse mutant and littermate WT mice (a–d), and that of the Nlgn3^mf mutant and littermate WT mice (e–h) were examined by eight-arm radial maze test. a, c, e, g, Number of different arm choices among the first 8 entries. b, d, f, h Latency to take all pellets. A delay was applied after the first 4 pellets were consumed (c, d, g, h). All values are presented as the mean ± SEM. There was no significant deference in different arm choices and latency to take all pellets between WT and Nlgn3^hse mutant mice, and between WT and Nlgn3^mf mutant mice. Summary statistics are shown in each panel