Time series of bursting activity drawn by using the data for the experimentsA and computer simulations at different temperatures. Experimentallyrecorded spike trains (blue, dotted line) and the result from computersimulations of modeling (red, solid line) are compared. The results fromsimulation using the equations developed by Canavier et al. [] and modified by us with temperature-dependent scaling factors atthe temperatures, 18.1°C, 22.1°C and 27.8 are shown on panels L1, M1,and H1 respectively, in the upper traces (A). Those using the modelsrevised by Butera et al. [] and Bertram [] and modified by us with the same temperature dependent scalingfactors are shown in the intermediate traces (B, C). The comparison of those using the equations revised by Bertram andmodified by us are shown in the lowest panels (D) at the temperatures22.2°C, 23.4°C and 25.8°C with small range of temperaturechanges.