Expression of functional inhibitory neurotransmitter transporters GlyT1, GAT-1, and GAT-3 by astrocytes of inferior colliculus and hippocampus

Table 3 The effect of glycine and GABA on astrocytic and neuronal membrane resistance

Region	Cell type	ΔR_{M (Gly)} [%]	P	ΔR_{M (GABA)} [%]	P
IC	Astrocyte	+8.4 ± 3.6 (15)	0.018 n.s. sc	+1.1 ± 4.4 (15)	0.403 n.s. sc
IC	Neuron	-97.9 ± 0.5 (11)	0.000 ***sc	−98.9 ± 0.1 (11)	0.000 ***sc
HC	Astrocyte	+2.9 ± 4.0 (6)	0.252 n.s. sc	−7.6 ± 1.1 (8)	0.000 ***sc
HC	Neuron	−41.2 ± 6.2 (4)	0.004 *sc	−73.5 ± 5.7 (5)	0.000 ***sc

The data are given as mean ± SEM. The number of experiments is given in parenthesis. IC Inferior colliculus, HC Hippocampus, P Probability value, sc Šidák corrected significance level for 3 comparisons, n.s. Not significant, *sc: P < 0.017, ***sc: P < 0.0003. For critical significance levels, see Methods section. ΔR_M is given for t₁ (1 s after focal application of neurotransmitter)

ISSN: 1756-6606