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Fig. 2 | Molecular Brain

Fig. 2

From: 5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

Fig. 2

ME-induced decrease in total 5-HT concentration in the adult visual cortex. a, b HPLC chromatogram of respectively the standard and a cortical sample. The peaks were numbered from 1 to 7 and represent noradrenaline; 3,4-dihydroxybenzylamine; 3,4-dihydroxyphenylacetic acid; dopamine; 5-hydroxy-indoleacetic acid; homovanillic acid and serotonin (5-HT). c In the visual cortex (VC) of 7wME mice (n = 6), a significantly decreased total 5-HT concentration was observed compared to AMC mice (n = 9, p = 0.018, Mann-Whitney test). d The primary somatosensory barrel field (S1BF) did not show a significant difference (p = 0.114, Mann-Whitney test). These results indicate an ME-induced effect on 5-HT signaling in sensory deprived cortex. The number of animals (n) is represented in the bars. *P < 0.05

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Molecular Brain

ISSN: 1756-6606